Systematic versus cognitive targeted biopsy: evaluation of parameters related to clinically significant prostate cancer and comparison of detection rates

Objective: This study aims to compare the clinically significant prostate cancer (csPCa) detection rates of cognitive targeted biopsy (CTB) and systematic (SB) reveal factors affecting csPCa rates. Material Methods: Patients diagnosed with localized between 2016-2019 were evaluated retrospectively. who underwent SB concomitant CTB recorded. The number cores taken from index lesion in CTB, age, prostate-specific antigen (PSA) level, Gleason score, International Society Urological Pathology (ISUP) grade, Prostate Imaging Data Reporting System (PIRADS) diameter lesion, digital rectal examination (DRE) findings was We also studied whether there a concordance localization on MRI (magnetic resonance imaging) nodule detected DRE. Results: Eighty patients included study. 55 (68.7%) SB, whereas alone 35 (43.7%) (p<0,01). missed 2 csPCa, but 35% men would be by CTB. Detection significantly higher DRE mpMRI (p= 0.012 p<0.01, respectively). In had differences mean volume, PSA, diameter, cores, PIRADS score (p=0.005, p=0.02, p=0.005, p=0.003, p=0.017, p=0.002, respectively) Conclusion: maintains its importance diagnosis csPCa. can preferred larger lesions. Keywords: cancer, biopsy, magnetic imaging,